Semantics concerns the study of meanings. Semantic interoperability is the ability of computer systems to transmit data with unambiguous, shared meaning. Semantic interoperability is a requirement to enable machine computable logic, inferencing, knowledge discovery, and data federation between information systems.

Information technology for learning, education and training -- Language accessibility and human interface equivalencies (HIEs) in e-learning applications -- Part 1: Framework and reference model for semantic interoperability

ISO/IEC 20016-1:2014 states the principles, rules and metadata elements for specifying language accessibility and Human Interface Equivalents (HIEs) in e-learning environments. It is structured to be able to support the requirements of applicable jurisdictional domains and in particular that of the UN Convention on the Rights of Persons with Disabilities.